My ME/CFS Recovery in Objective Microbiome Measurements

For more analysis of ME/CFS and Long COVID see this list.

Percentile’s Percentage

Below are my numbers during a flare — I had the typical over-representation of 0-9%ile seen in most ME/CFS and Long-COVID samples.

After going into Remission, the low percentile counts dropped massively

Alpha Diversity

During Flare

After going into Remission, the two Diversity Index increases significantly. Common belief is that the higher the diversity indices, the better it is for a person. Diversity index typically decreases with age as age related conditions increase.

Dr. Jason Hawrelak Recommendations did not reflect the change. At 98.8%ile during the flare and dropping to 89%ile with remission.

In the Bacteria Deem Unhealthy, Rickettsia was at 77%ile, Legionella was 100% and our anti-inflammation bacteria Faecalibacterium prausnitzii was done to 16%ile [Human CD4+CD8α+ Tregs induced by Faecalibacterium prausnitzii protect against intestinal inflammation]. With remission the first two bacteria disappeared and Faecalibacterium prausnitzii went up to 87%ile.

Seeing the Rickettsia spike reminds me of Cecile Jadin’s work from the 1990’s where this bacteria was very frequently identified in ME/CFS patients using specialized tests.

Bottom Line

We have some clear patterns associated with ME/CFS and Long COVID. It is my belief that the microbiome is a very significant player in this condition and that by correcting abnormal shifts by diet, supplements, antibiotics, etc, remission is probable for many. How to correct is very specific to an individual’s microbiome. There is no universal protocol.

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