Caveat: Suggestions

Suggestions are items computed to have a higher probability of success in altering the microbiome. The computation is done using artificial intelligence on a “fact database” consisting of over a million facts obtained from published studies (PubMed Studies usually)

Suggestions should be reviewed by a medical professional familiar with you before implementing. Some suggestions may have adverse reactions with some conditions. The suggestions are built using published research on humans and animals. The suggestions may not be applicable to humans.

The HIGHEST confidence values are the ones with the most studies usually. The highest confidence of actually doing shifting the targeted bacteria in the correct direction. It is NOT the magnitude of change or probability of helping.

This may explain what is meant by confidence.

  • If grapes are reported in 10 studies as helping, it may end up being a 1.0 because there is great confidence in it having an impact
  • If salmonberries are reported in 1 studies as helping, it may end up being a 0.1 – but it could be 10 times as effective… but because the study have not been replicated, we are less certain of it.
  • In the studies that help, 6 out of 10 patients may be helped. That is the probability of helping. We do not have that information (often not published).
  • Some studies may say that it decreases some lab measure X by 10%, other studies says it decreased the same lab measure X by 50%. That is the magnitude of change. We do not have that information (often not published).

There is NO data on relative effectiveness.

  • Suggestions can be based on the ideal ranges for key bacteria from Dr. Jason Hawrelak , based in Tasmania, Australia. He is well respected and has a 2+ year waiting list for new patients. The ranges are used with his permission. And is the best available holistic definition of a good general microbiome and is a good starting point for newbies to the microbiome. 
  • Other suggestions on from Artificial Intelligence using various algorithms and a lot of data. There are not from Dr. Hawrelak.

This site provides many specialized approaches to select the relevant bacteria for specific symptoms. These alternative approaches are more complex to understand, are often driven by people speculation on what is important. There is no IDEAL, APPLIES TO ALL approach.

Dosage Advise

We do not provide dosages on this site. On an associated site, CFS Remission, some dosages are given selectively. On that site, all of the dosages are based on the dosages used in studies on humans reported on Pub Med. If you wish to find a dosage, you will need to search that site or ask your knowledgeable medical professional. Sorry…. too much liability risk.

Supplements Advice

Commercial supplements (especially herbs and spices) are rarely organic and usually full of fillers. Many people are sensitive to the fillers and misassociate their reaction to the supplements.

Our suggested approach is to buy in bulk organic herbs, spices, etc and create your own capsules. These commercial supplements the cost per gram may be 4x to 50x higher than buying in bulk and making your own capsules.
NOTE: Many folks have reported things did not help until they change to a different brand with different fillers.

For probiotics, we usually avoid common commercial mixtures. Why? Often they are mislabeled. Often they contain helping and hurting probiotics for a specific person’s microbiome. Lastly, the cost (like supplements) can be 4x to 50x higher than buying in bulk the same probiotics (without fillers!). Our usual source is Custom Probiotics.

Contradictory Suggestions

I have seen lactobacillus rhamnosus gg (probiotics) being a TO TAKE and lactobacillus rhamnosus (probiotics) is to avoid. Why? Different studies have different results.

  • Sometimes it is because of other factors (study done on healthy people in one case, on overweight people in the other case).
  • One study may have measured the bacteria you are high in, the other did not.
  • Similarly, one study may have measured the bacteria you are low in, the other did not.
  • Where there are ‘conflicts’, my usual advice is to just omit it entirely from consideration. If you are taking it, keep taking it. It not, don’t.

There is a forest of qualifications that are nearly impossibly complex to address, and if you try, it will often lack an objective decision that can be demonstrated (“I think….”).

Bottom Line

This is a citizen science site exploring available studies. It does not make any recommendations on treatments. It does make suggestions for items to discuss with well qualified medical professionals; items that appears to have a higher probability of helping.