Ombre Suggestions Analysis – Failing Grade

This is part 2A of Comparing Microbiomes from Three Different Providers – Part 1. I decided to do each lab separately and then do an overview at the end.


It is very simple, look at their suggestions, look at any references they provided. Then look at Microbiome Prescription evidence trail for the same substances. My usual “Just the facts, ma’am” approach. This data was retrieved on 24 Aug 2023.

They recommended their own brand mixture

Then we asked for suggests with no diet and no allergies.

At this point, I deem their evidence is grossly insufficient. Not one solid piece of evidence in almost 30 “scientific evidence”. I will say myself frustration (and the reader boredome) .

Using Microbiome Prescription Evidence

Most of the studies cited above were references to FODMAP, either low or high with this being ignored.

  • Multivariate modelling of faecal bacterial profiles of patients with IBS predicts responsiveness to a diet low in FODMAPs. Gut (Gut ) Vol: 67 Issue 5 Pages: 872-881 Pub: 2018 May Epub: 2017 Apr 17 Authors Bennet SMP , Böhn L , Störsrud S , Liljebo T , Collin L , Lindfors P , Törnblom H , Öhman L , Simrén M ,

For Tagliatelle (Pasta), we find the following study with adverse effect on many bacteria (it was an avoid)

  • Carbohydrate Staple Food Modulates Gut Microbiota of Mongolians in China. Frontiers in microbiology (Front Microbiol ) Vol: 8 Issue Pages: 484, Pub: 2017 Epub: 2017 Mar 21 Authors Li J , Hou Q , Zhang J , Xu H , Sun Z , Menghe B , Zhang H ,

Yuzu (Yuzu is a citrus fruit). This is not in the database, but another citric food is there, and it is a take suggestion

  • Analysis of Temporal Changes in Growth and Gene Expression for Commensal Gut Microbes in Response to the Polyphenol Naringenin. Microbiology insights (Microbiol Insights ) Vol: 11 Issue Pages: 1178636118775100 Pub: 2018 Epub: 2018 May 30 Authors Firrman J , Liu L , Argoty GA , Zhang L , Tomasula P , Wang M , Pontious S , Kobori M , Xiao W 
  •  The inhibitory effect of polyphenols on human gut microbiota. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (J Physiol Pharmacol ) Vol: 63 Issue 5 Pages: 497-503 Pub: 2012 Oct Epub: Authors Duda-Chodak A ,

For beans — we have the same citation to bean and soy tempeh 

For Garlic, we have it as an avoid with the following studies being the basis

  •  Effect of garlic powder on the growth of commensal bacteria from the gastrointestinal tract.
    Phytomedicine : international journal of phytotherapy and phytopharmacology (Phytomedicine ) Vol: 19 Issue 8-9 Pages: 707-11 Pub: 2012 Jun 15 Epub: 2012 Apr 4 Authors Filocamo A , Nueno-Palop C , Bisignano C , Mandalari G , Narbad A ,
  • Dietary prophage inducers and antimicrobials: toward landscaping the human gut microbiome.
    Gut microbes (Gut Microbes ) Vol: Issue Pages: 1-14 Pub: 2020 Jan 13 Epub: 2020 Jan 13 Authors Boling L , Cuevas DA , Grasis JA , Kang HS , Knowles B , Levi K , Maughan H , McNair K , Rojas MI , Sanchez SE , Smurthwaite C , Rohwer F
  • Inhibitory activity of garlic (Allium sativum) extract on multidrug-resistant Streptococcus mutans.
    Journal of the Indian Society of Pedodontics and Preventive Dentistry (J Indian Soc Pedod Prev Dent ) Vol: 25 Issue 4 Pages: 164-8 Pub: 2007 Oct-Dec Epub: Authors Fani MM , Kohanteb J , Dayaghi M 
  •  Effects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice.
    Pharmaceutical biology (Pharm Biol ) Vol: 56 Issue 1 Pages: 325-332 Pub: 2018 Dec Epub: Authors Wang Y , Guan M , Zhao X , Li X 
  • Black garlic melanoidins prevent obesity, reduce serum LPS levels and modulate the gut microbiota composition in high-fat diet-induced obese C57BL/6J mice. Food & function (Food Funct ) Vol: 11 Issue 11 Pages: 9585-9598 Pub: 2020 Nov 18 Epub: Authors Wu J , Liu Y , Dou Z , Wu T , Liu R , Sui W , Jin Y , Zhang M 

Their recommended probiotic contains the following species (with the evidence based suggestions count after):

  • L. Acidophilus – Mixed impact (2 plus, 1 minus)
  • E. Faecium – Avoid (3 minus)
  • L. Paracasei – MAJOR Avoid ( 4 minus)
  • L. Helveticus – Avoid ( 3 minus, 1 plus)
  • L. Rhamnosus – Mixed (2 plus, 2 minus)
  • L. Plantarum – MAJOR Avoid (4 minus)
  • B. Lactis – MAJOR Avoid (4 minus)
  • S. Boulardi – Mixed (2 plus, 2 minus)

IMHO, this is NOT a good mixture to take.

Bottom Line

Ombre’s suggestions for both probiotic and diet style leaves great opportunity to be made better. Their scientific citations is almost an embarrassment. I suspect that they were contracted out to a dietician and had no or poor quality control/review.

The videos below shows how you can see the evidence for the suggestions on Microbiome Prescription.