Risks of high Lactobacillus and Bifidobacterium

This post started from reading “Dietary quality and the gut microbiome in early-stage Parkinson’s disease patients [2023]”. I posted on some Facebook groups “People often are obsessives with getting high Lactobacillus and Bifidobacterium. The “dividend” of this desire appears to be increased risk of Parkinson’s disease.

The question arises, what other conditions are associated with high levels of both of these? Fortunately, this can be obtained from the Microbiome Prescription databases.

  • Amyotrophic lateral sclerosis (ALS) Motor Neuron
  • Autism
  • Crohn’s Disease
  • Depression
  • Graves’ disease
  • Inflammatory Bowel Disease
  • Irritable Bowel Syndrome
  • Juvenile idiopathic arthritis
  • Liver Cirrhosis
  • Long COVID
  • Metabolic Syndrome
  • Mood Disorders
  • Multiple Sclerosis
  • Obesity
  • Parkinson’s Disease
  • Psoriasis
  • rheumatoid arthritis (RA),Spondyloarthritis (SpA)
  • Schizophrenia
  • Stress / posttraumatic stress disorder
  • Type 2 Diabetes
  • Ulcerative colitis

I also pulled the studies where the study specifically cited both are high. The above list were occasionally from taking data from two different studies.

Bottom Line

A responsible medical professional would test a patient’s Lactobacillus and Bifidobacterium levels before suggesting probiotics to a patient. If your MD makes that recommendation without testing and you have any of the above conditions — it may be time to file a complaint with their supervisors or governing body citing the studies.