These are notes in progress. Use them at your own risk
In terms of KEGG data, one enzyme stands out: ATP:L-threonine O3-phosphotransferase (18.104.22.168). This is referred to as L-threonine in simpler terms. The people with this sensitivity has 10% of the levels of people not reporting it and there is a value for almost every sample.
This lead to this interest quote (dealing with plants)
- “Salicylic acid[SA] .. in the rhizosphere may be strongly reduced, or completely abolished, due to the presence of histidine and threonine in the root exudates.”  in other threonine may be a key chemical is processing SA.
Checking for the bacteria known to produce the EC22.214.171.124 ATP:L-threonine O3-phosphotransferase the top 3 are:
- Clostridium difficile [species] at 639
- Veillonella dispar [species] at 554
- Megamonas funiformis [species] at 534
- Megasphaera elsdenii [species] at 392
There are no probiotics that produces it. It is available as a supplement, with WebMd suggests this dosage of “Early research suggests that taking 1.5 grams to 2 grams of threonine by mouth three times daily might improve some symptoms in people with familial spastic paraparesis. But the improvement does not seem to be very significant.”
I was unable to find anyone trying this for Salicylate Sensitivity (Hint: any volunteers?)
I did an analysis looking at the frequency percentage of a bacteria being found for Biomesight samples (the largest collection). The key items are below. The higher the Chi2 value, the more likely it is.
|Ruminococcus callidus||species||24.1 (Under)||56.3||5.3|
(in Staphylococcaceae family)
There was not sufficient data on Ombre samples
The substances that reduces these overgrowths are: Cacao, green tea, kefir, lychee fruit, papaya, rhubarb, rosehip tea, trametes versicolor(Turkey tail mushroom), Slippery Elm. Many of these are low in salicylate (check each one before doing).
I did an analysis looking at the frequency percentage of a bacteria being found for Biomesight samples (the largest collection). The statistically significant items are below, with 1 overgrowth “Streptococcus oralis” and the rest as undergrowth . The higher the Chi2 value, the more likely it is.
|Streptococcus oralis subsp. tigurinus||subspecies||57.9||43.7||5.13|