Today I ran some queries to see how many progressions between the conditions that I have could be inferred from the current data. The following were used:

• The taxon must be exact matches (no parent of a taxa or taxa children)
• We count the number of times that the taxa shifts are the same direction, or are different
• Each condition must share at least 10 bacteria.
• All of the data (with sources) can be found here for people to dig further into relationships.

The results are below for those with 65% the same or more. Some are very expected, some are not

• Chronic Fatigue Syndrome with
  • ME/CFS with IBS
  • ME/CFS without IBS
  • ME/CFS with IBS vs ME/CFS without IBS DOES NOT SHOW UP because they only have 5 bacteria in common
• Small Intestinal Bacterial Overgrowth  (SIBO) was not expected with
  • Colorectal Cancer
  • Rheumatoid Arthritis (RA),Spondyloarthritis (SpA)
  • Parkinson’s Disease
  • But expected with Irritable Bowel Syndrome
    
  • NOTE: Progression from one condition to another condition may be depend on DNA or epigenetics. If there is a high match up, it should be viewed as increased risk that may be mitigated with adjustments of the microbiome.

Condition Name	Condition Name	Same Direction Percentage	Different Direction Percentage
Alzheimer’s disease	Chronic Kidney Disease	86.7	13.3
ADHD	Chronic Kidney Disease	85.7	14.3
Chronic Fatigue Syndrome	ME/CFS with IBS	85.7	14.3
Chronic Urticaria (Hives)	Obesity	85.7	14.3
Chronic Fatigue Syndrome	ME/CFS without IBS	85.2	14.8
Chronic Urticaria (Hives)	obsessive-compulsive disorder	84.6	15.4
Chronic Urticaria (Hives)	Ulcerative colitis	83.3	16.7
Colorectal Cancer	Small Intestinal Bacterial Overgrowth  (SIBO)	83.3	16.7
Histamine Issues,Mast Cell Issue, DAO Insufficiency	obsessive-compulsive disorder	83.3	16.7
Brain Trauma	hypertension (High Blood Pressure	83.3	16.7
Allergic Rhinitis (Hay Fever)	Chronic Fatigue Syndrome	83.3	16.7
Ankylosing spondylitis	Rosacea	83.3	16.7
Parkinson’s Disease	Anorexia Nervosa	83.3	16.7
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	Small Intestinal Bacterial Overgrowth  (SIBO)	83.3	16.7
Brain Trauma	Multiple Sclerosis	81.8	18.2
Hyperlipidemia (High Blood Fats)	Multiple Sclerosis	81.8	18.2
hypertension (High Blood Pressure	Nonalcoholic Fatty Liver Disease  (nafld) Nonalcoholic	81.8	18.2
Graves’ disease	Bipolar Disorder	81.8	18.2
Chronic Urticaria (Hives)	Inflammatory Bowel Disease	81.3	18.8
Stress / posttraumatic stress disorder	Systemic Lupus Erythematosus	80.8	19.2
ME/CFS without IBS	Long COVID	80	20
Chronic Kidney Disease	Bipolar Disorder	80	20
Alzheimer’s disease	Multiple Sclerosis	80	20
ADHD	obsessive-compulsive disorder	78.6	21.4
gallstone disease (gsd)	Ulcerative colitis	78.6	21.4
Osteoarthritis	Long COVID	78.6	21.4
Systemic Lupus Erythematosus	Anorexia Nervosa	77.8	22.2
ADHD	Multiple Sclerosis	77.3	22.7
Chronic Urticaria (Hives)	Nonalcoholic Fatty Liver Disease  (nafld) Nonalcoholic	76.9	23.1
Parkinson’s Disease	Small Intestinal Bacterial Overgrowth  (SIBO)	76.9	23.1
Chronic Urticaria (Hives)	Long COVID	76.5	23.5
Gastroesophageal reflux disease (Gerd) including Barrett’s esophagus	Long COVID	76.5	23.5
Chronic Kidney Disease	Systemic Lupus Erythematosus	76.2	23.8
hypertension (High Blood Pressure	obsessive-compulsive disorder	76	24
Inflammatory Bowel Disease	Small Intestinal Bacterial Overgrowth  (SIBO)	75	25
Histamine Issues,Mast Cell Issue, DAO Insufficiency	Schizophrenia	75	25
Multiple Sclerosis	Small Intestinal Bacterial Overgrowth  (SIBO)	75	25
Nonalcoholic Fatty Liver Disease  (nafld) Nonalcoholic	Stress / posttraumatic stress disorder	75	25
Chronic Kidney Disease	Graves’ disease	75	25
gallstone disease (gsd)	Nonalcoholic Fatty Liver Disease  (nafld) Nonalcoholic	75	25
Cerebral Palsy	Parkinson’s Disease	75	25
Rosacea	Type 1 Diabetes	75	25
Chronic Urticaria (Hives)	Crohn’s Disease	73.7	26.3
Chronic Urticaria (Hives)	Psoriasis	72.7	27.3
Depression	ME/CFS with IBS	72.7	27.3
neuropsychiatric disorders (PANDAS, PANS)	Parkinson’s Disease	72.7	27.3
Irritable Bowel Syndrome	Osteoarthritis	72.7	27.3
Histamine Issues,Mast Cell Issue, DAO Insufficiency	Inflammatory Bowel Disease	72.7	27.3
Chronic Fatigue Syndrome	Functional constipation / chronic idiopathic constipation	72.7	27.3
Asthma	Celiac Disease	72.7	27.3
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	Hidradenitis Suppurativa	72.7	27.3
ADHD	Alzheimer’s disease	72.2	27.8
Allergies	Psoriasis	72.2	27.8
Brain Trauma	Parkinson’s Disease	72.2	27.8
Depression	Fibromyalgia	72.2	27.8
Atherosclerosis	Histamine Issues,Mast Cell Issue, DAO Insufficiency	72	28
Inflammatory Bowel Disease	Ulcerative colitis	71.8	28.2
Chronic Kidney Disease	Stress / posttraumatic stress disorder	71.4	28.6
Atherosclerosis	ME/CFS with IBS	71.4	28.6
ADHD	Functional constipation / chronic idiopathic constipation	71.4	28.6
Ankylosing spondylitis	Gastroesophageal reflux disease (Gerd) including Barrett’s esophagus	71.4	28.6
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	Rosacea	71.4	28.6
Chronic Kidney Disease	Long COVID	70.6	29.4
gallstone disease (gsd)	rheumatoid arthritis (RA),Spondyloarthritis (SpA)	70.6	29.4
Multiple Sclerosis	Anorexia Nervosa	70.6	29.4
Inflammatory Bowel Disease	Nonalcoholic Fatty Liver Disease  (nafld) Nonalcoholic	70.4	29.6
hypertension (High Blood Pressure	Inflammatory Bowel Disease	70	30
Cerebral Palsy	Long COVID	70	30
Chronic Kidney Disease	COVID-19	69.6	30.4
Cerebral Palsy	obsessive-compulsive disorder	69.2	30.8
Cerebral Palsy	Psoriasis	69.2	30.8
Atherosclerosis	Osteoarthritis	69.2	30.8
Bipolar Disorder	obsessive-compulsive disorder	69.2	30.8
ADHD	Anorexia Nervosa	69.2	30.8
Alzheimer’s disease	Anorexia Nervosa	69.2	30.8
Hyperlipidemia (High Blood Fats)	rheumatoid arthritis (RA),Spondyloarthritis (SpA)	69.2	30.8
hypertension (High Blood Pressure	Osteoporosis	69.2	30.8
Inflammatory Bowel Disease	Anorexia Nervosa	69.2	30.8
Nonalcoholic Fatty Liver Disease  (nafld) Nonalcoholic	Anorexia Nervosa	69.2	30.8
Nonalcoholic Fatty Liver Disease  (nafld) Nonalcoholic	Ulcerative colitis	69.2	30.8
Fibromyalgia	Nonalcoholic Fatty Liver Disease  (nafld) Nonalcoholic	69.2	30.8
Chronic Kidney Disease	Nonalcoholic Fatty Liver Disease  (nafld) Nonalcoholic	69.2	30.8
Chronic Kidney Disease	Osteoporosis	69.2	30.8
Chronic Kidney Disease	Inflammatory Bowel Disease	68.8	31.3
Chronic Kidney Disease	Multiple Sclerosis	68.8	31.3
gallstone disease (gsd)	Irritable Bowel Syndrome	68.8	31.3
ME/CFS with IBS	COVID-19	68.8	31.3
Irritable Bowel Syndrome	Small Intestinal Bacterial Overgrowth  (SIBO)	68.8	31.3
hypertension (High Blood Pressure	Bipolar Disorder	68.8	31.3
Allergic Rhinitis (Hay Fever)	Systemic Lupus Erythematosus	68.8	31.3
Atherosclerosis	Small Intestinal Bacterial Overgrowth  (SIBO)	68.8	31.3
Chronic Kidney Disease	Colorectal Cancer	68.8	31.3
Chronic Kidney Disease	Depression	68.4	31.6
gallstone disease (gsd)	COVID-19	68.4	31.6
Atherosclerosis	Liver Cirrhosis	68.3	31.7
Ankylosing spondylitis	Liver Cirrhosis	68.2	31.8
Celiac Disease	Inflammatory Bowel Disease	68.2	31.8
Functional constipation / chronic idiopathic constipation	Schizophrenia	68.2	31.8
Stress / posttraumatic stress disorder	Ulcerative colitis	68.1	31.9
Ankylosing spondylitis	Bipolar Disorder	67.9	32.1
ADHD	Depression	67.9	32.1
Alzheimer’s disease	Parkinson’s Disease	67.6	32.4
Ulcerative colitis	Long COVID	67	33
Osteoarthritis	rheumatoid arthritis (RA),Spondyloarthritis (SpA)	66.7	33.3
Osteoporosis	COVID-19	66.7	33.3
Alzheimer’s disease	Insomnia	66.7	33.3
Amyotrophic lateral sclerosis (ALS) Motor Neuron	Bipolar Disorder	66.7	33.3
Alzheimer’s disease	Bipolar Disorder	66.7	33.3
Anorexia Nervosa	Long COVID	66.7	33.3
Anorexia Nervosa	obsessive-compulsive disorder	66.7	33.3
Asthma	Systemic Lupus Erythematosus	66.7	33.3
ADHD	Bipolar Disorder	66.7	33.3
Allergic Rhinitis (Hay Fever)	Stress / posttraumatic stress disorder	66.7	33.3
ADHD	Chronic Fatigue Syndrome	66.7	33.3
Acne	Stress / posttraumatic stress disorder	66.7	33.3
Acne	Systemic Lupus Erythematosus	66.7	33.3
Acne	Liver Cirrhosis	66.7	33.3
Allergic Rhinitis (Hay Fever)	Sjögren syndrome	66.7	33.3
Allergies	Type 1 Diabetes	66.7	33.3
Cerebral Palsy	Ankylosing spondylitis	66.7	33.3
Chronic Fatigue Syndrome	Nonalcoholic Fatty Liver Disease  (nafld) Nonalcoholic	66.7	33.3
Cerebral Palsy	Systemic Lupus Erythematosus	66.7	33.3
Cerebral Palsy	Inflammatory Bowel Disease	66.7	33.3
Brain Trauma	Type 2 Diabetes	66.7	33.3
Brain Trauma	obsessive-compulsive disorder	66.7	33.3
Brain Trauma	Irritable Bowel Syndrome	66.7	33.3
Fibromyalgia	obsessive-compulsive disorder	66.7	33.3
gallstone disease (gsd)	Stress / posttraumatic stress disorder	66.7	33.3
Depression	Gout	66.7	33.3
Chronic Kidney Disease	obsessive-compulsive disorder	66.7	33.3
Chronic Urticaria (Hives)	Systemic Lupus Erythematosus	66.7	33.3
Crohn’s Disease	Histamine Issues,Mast Cell Issue, DAO Insufficiency	66.7	33.3
COVID-19	Eczema	66.7	33.3
Histamine Issues,Mast Cell Issue, DAO Insufficiency	Liver Cirrhosis	66.7	33.3
Insomnia	Long COVID	66.7	33.3
Inflammatory Bowel Disease	obsessive-compulsive disorder	66.7	33.3
Inflammatory Bowel Disease	Osteoarthritis	66.7	33.3
Inflammatory Bowel Disease	ME/CFS without IBS	66.7	33.3
ME/CFS with IBS	Ulcerative colitis	66.7	33.3
ME/CFS without IBS	COVID-19	66.7	33.3
Liver Cirrhosis	neuropsychiatric disorders (PANDAS, PANS)	66.7	33.3
Liver Cirrhosis	ME/CFS with IBS	66.7	33.3
Multiple Sclerosis	Multiple system atrophy (MSA)	66.7	33.3
Liver Cirrhosis	Stress / posttraumatic stress disorder	66	34
Inflammatory Bowel Disease	rheumatoid arthritis (RA),Spondyloarthritis (SpA)	65.9	34.1
Celiac Disease	obsessive-compulsive disorder	65.7	34.3
Celiac Disease	Systemic Lupus Erythematosus	65.6	34.4
Chronic Fatigue Syndrome	Schizophrenia	65.5	34.5
hypertension (High Blood Pressure	COVID-19	65.5	34.5
ADHD	Parkinson’s Disease	65.4	34.6
Sjögren syndrome	Systemic Lupus Erythematosus	65.4	34.6
Stress / posttraumatic stress disorder	obsessive-compulsive disorder	65.2	34.8
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	Bipolar Disorder	65.2	34.8
Chronic Fatigue Syndrome	Parkinson’s Disease	65.2	34.8
Autism	Brain Trauma	65.2	34.8
Multiple Sclerosis	Parkinson’s Disease	65.2	34.8
Atherosclerosis	IgA nephropathy (IgAN)	65	35
Asthma	COVID-19	65	35
Chronic Kidney Disease	rheumatoid arthritis (RA),Spondyloarthritis (SpA)	65	35
Alzheimer’s disease	Graves’ disease	65	35