Cancer Patient under Treatment – the Microbiome connection

This is a change from the usual microbiome. The microbiome has impact on getting cancers and on the effectiveness of various treatments. A little bit of recent literature is below.

Analysis

This person is atypical — they find the markers for cancer, but cannot locate where it is.
We see a large number of bacteria with only token representation (0-9 Percentile). Statistically, you would expect each of the ranges below to have similar numbers.

PercentileGenusSpecies
0 – 97391
10 – 191614
20 – 291421
30 – 391920
40 – 491221
50 – 591618
60 – 69823
70 – 791127
80 – 893320
90 – 992232

The new feature “Likely Key Bacteria Causing Above’ show items of concern:

RankBacteriaImportance
genusMegasphaera2.6
speciesMegasphaera elsdenii2.5
genusKlebsiella2.2
speciesKlebsiella oxytoca2.1
genusBifidobacterium1.9
Video on the new features (not for this analysis)

From the Potential Medical Conditions Detected, we see gut disturbances (Gastroesophageal reflux disease (Gerd) including Barrett’s esophagus, Histamine Issues,Mast Cell Issue, DAO Insufficiency) as well as neurological impacts (Brain Trauma, Epilepsy).

Looking at Bacteria deemed Unhealthy, we have the following with significant counts and percentiles.

NameRankPercentileCountCommentMore Info
Collinsellagenus9815880proinflammatoryCitation
Enterobactergenus9812700Urinary and respiratory infectionsCitation
Klebsiellagenus10074750PathogenCitation
Parabacteroides merdaespecies9424150Infectious bacteriaCitation
Prevotella coprispecies761990Over 70%ile Indicator of mycotoxin presentCitation
Salmonella entericaspecies98600SalmonellosisCitation
Most interesting ones

The Prevotella copri may indicate a mold/fungi issue in the house, or it could be a side effect of the immune system being impacted by treatment.

Dr. Jason Hawrelak Recommendations is at 89%ile with the main items well out of range being:

Going Forward

Doing consensus building with following criteria:

The new “just give me suggestions” had the following being clear thumbs up:

Remember they are suggestions — just pick items that you can afford, can get, and that you are happy taking.

The list of items to take was actually surprising. It was a large list with all 4 sets of suggestions saying take (over 110!) . The top items are below

  • foeniculum vulgare (Fennel)
  • Curcumin
  • Vitamin B-12
  • syzygium aromaticum (clove)
  • Hesperidin (polyphenol)
  • garlic (allium sativum)
  • nigella sativa seed (black cumin)
  • Caffeine
  • thiamine hydrochloride (vitamin B1)
  • oregano (origanum vulgare, oil)
  • Arbutin (polyphenol)
  • diosmin,(polyphenol)
  • pyridoxine hydrochloride (vitamin B6)
  • retinoic acid,(Vitamin A derivative)
  • thyme (thymol, thyme oil)
  • luteolin (flavonoid)
  • kefe cumin (laser trilobum l.)
  • neem

On the avoid list we have many items which for other people tend to be on their take list

Going over to the Food site, we see the following items near the top: Kidney, marmite, Cream of Wheat. The main reason is that they are high in B vitamins.

Postscript – and Reminder

I am not a licensed medical professional and there are strict laws where I live about “appearing to practice medicine”.  I am safe when it is “academic models” and I keep to the language of science, especially statistics. I am not safe when the explanations have possible overtones of advising a patient instead of presenting data to be evaluated by a medical professional before implementing.

I cannot tell people what they should take or not take. I can inform people items that have better odds of improving their microbiome as a results on numeric calculations. I am a trained experienced statistician with appropriate degrees and professional memberships. All suggestions should be reviewed by your medical professional before starting.

The answers above describe my logic and thinking and is not intended to give advice to this person or any one. Always review with your knowledgeable medical professional.