Bacteria Shifts Seen in Long COVID

There is a Long COVID Study in progress via the cooperation BiomeSight.com and Microbiome Prescrption. The data is not yet processed for the study, but we have some interest results already from those that uploaded their samples and marked Long COVID as a symptom.

BacteriaTaxonomy
Rank
Average
Percentile
Frequency Seen
in this Group
Frequency Seen
in All Samples
Micrococcaceaefamily1945.836.5
Actinobacteriaphylum19.710099.7
cellular organismsnorank2010099.9
Adlercreutzia equolifaciensspecies20.162.542.8
Peptostreptococcaceaefamily22.895.896.5
Butyricimonas virosaspecies23.341.738.8
Sarcinagenus24.745.852.4
Enterobactergenus25.141.723.6
Lactobacillaceaefamily2695.894.9
Coriobacteriiaclass2710099
Actinomycetiaclass27.610099.2
Adlercreutziagenus27.866.745.3
Slackia faecicanisspecies2837.511.8
Bifidobacterium adolescentisspecies28.179.231.4
Rhodovibrionaceaefamily28.437.50
Blautia wexleraespecies29.210094.4
Anaerostipesgenus29.795.896.1
Salinicoccus luteusspecies30.937.512.6
Staphylococcaceaefamily30.962.540.4
Bifidobacterialesorder31.210089.7
Holdemanella biformisspecies31.366.732.7
Coriobacterialesorder31.310095.7
Holdemanellagenus31.466.732.8
Eubacteriales incertae sedisnorank31.595.889.5
Bifidobacteriaceaefamily31.710089.6
Fusobacteriaphylum31.745.840.8
Fusobacteriiaclass31.845.840.7
Eggerthellalesorder31.810097
Eggerthellaceaefamily31.910097
Terrabacteria groupclade31.910099.9
Fusobacterialesorder3245.840.7
Collinsellagenus3291.789.4
Leuconostocaceaefamily3262.554.4
Coriobacteriaceaefamily32.710094.7
Bifidobacteriumgenus3310088.2
Pseudobutyrivibriogenus33.279.281.6
Turicibacter sanguinisspecies33.862.555.5
Bacteroides denticanumspecies34.270.821.9
Fusobacteriumgenus34.241.733.9
Erysipelotrichaceaefamily34.410098.8
Doreagenus34.410098.3
Natranaerobialesorder34.554.221
Actinomycetaceaefamily34.687.582.5
Roseburia faecisspecies34.895.880.9
Veillonella montpellierensisspecies34.937.514.6
Holdemaniagenus65.795.877.6
Chlorobaculumgenus67.45020.2
Bacteroides ovatusspecies67.610073.9
Anaerotruncus colihominisspecies69.110065.8
Oscillospiragenus75.17555.5
Data on a Sample Size of 24

What is striking is not higher counts, but certain bacteria are being seen a lot more often. In fact, no bacteria is seen less often with Long COVID people but the amount may be less. That is more types of bacteria but with lower levels than average.

Note: Percentile means the percentile ranking of samples for a specific bacteria. The expected percentile for a random sample of people is 50%ile. Thus a lower percentile means that the median of the group is less than the median of the population. A higher percentile means that the median of the group is higher than the median of the population. The severe skewness of bacteria distribution does not mean the the average of the sample is lower or higher than the average of the population — in fact, they may be the same. (Welcome to statistical gymnastics 301!!!)

The ME/CFS Connection

This type of novel analysis (using frequency of detection and not amount of bacteria) results in Long COVID and Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). being very similar at the microbiome level. see Bacteria Shifts Seen in Chronic Fatigue Syndrome.

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