I work with several microbiome testing companies. These companies desire a reliable automated way of extracting data from studies. At the same time, I have been pinged by people claiming they can do it. My response is simple:
Show Me the Evidence
The easiest solution is to give a challenge set of data:
- All bacteria must be identified by NCBI Taxon Number (integer), not arbitrary name. The definitive source of this information is here.
- Warning: Spelling mistakes, former names, regional variations (i.e. color vs colour) are part of the problem
- The following conditions [ConditionId] should be searched for. Note that there are many alternative names in the literature.
- The following modifiers [ModifierId] should be searched for. Note that there are many alternative names in the literature.
A collection of open source studies are listed below [CitationId],[ConditionId],[ModifierId]
The expected submission are these Comma Separated Files
- Modifications.csv:
- taxon
- ModifierId
- CitationId
- Shift (+1 for increase, -1 for decrease, 0 for no impact)
- Conditions.csv
- taxon
- ConditionId
- CitationId
- Shift (+1 for high, -1 for low, 0 for no shift)
- Treatment.csv – only items that reduces the severity of the condition
- ModifierId
- CitationId
- ConditionId
The Source Files
Additional Data that would be desired:
- Experimental Subject (i.e. human, mice, zebra fish, etc)
- Qualification: (diabetes, obese, Parkinson, etc)
- Significance (P < 0.05, P < 0.0001)
- Sample Size
- Statistical Method Used
Submitting Results
Email the files to Research@MicrobiomePrescription.com with the files. A quote per 1000 documents should be included. The results will be forwarded to those that I am working with.
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