A reader with Multiple Chemistry Sensitivity(MCS) read my Light Sensitivity Exploration post and asked me to look at her sample because her MCS has been getting worse and she is hoping to slow and ideally reverse it. She does not want to become an anchorite with complete isolation from people. On her symptom list it is:
- Comorbid: Multiple Chemical Sensitivity
- Mast Cell Activation Syndrome (Next Post)
Looking at Comorbidity from our contributed data
- 14% of people with Photo Sensitivity have MCS, but 89% have MCAS/Histamine issues
- 17% of people with MCAS/Histamine issues have MCS, but 51% have Photo Sensitivity
| Photo Sensitivity | MCS | MCAS | |
| Photo Sensitivity | 427 | 60 | 383 |
| MCS | 238 | 135 | |
| MCAS | 753 |
I am going to skip the explorations that I did in the earlier post. As with prior post, Odds Ratio has better fine level identification.
| Classic | Odds Ratio | |
| Bacteria Considered | 85 | 103 |
| Bacteria In Common | 17 | 15 |
| Species | 6 | 37 |
| Genus | 16 | 35 |
| Family | 24 | 13 |
| Order | 17 | 10 |
| Class | 10 | 4 |
Since Light Sensitivity and MCS tends to go hand in hand, I did a comparison of the net Log(odd ratio) between people. A person without these issues is expected to have a Log(Odds Ratio) < 0. This Post’s anchorite has moderate light sensitivity in reality.
| Person | Light Sensitivity | MCS |
| Last Post Person | 11.8 | 17.3 |
| Anchorite | 5.7 | 16.4 |
This feature is now available on the web site for samples from Biomesight, Ombre, Thorne and uBiome. How to get to it and use it is shown below.
Probiotics Suggestions for MCS
The full list is below (remember only probiotic bacteria reported by Biomesight are included). The list for the Last Post person for MCS was very similar.
| Tax_name | Impact |
| Bifidobacterium longum | 2.22 |
| Bifidobacterium adolescentis | 1.92 |
| Enterococcus faecalis | 1.89 |
| Bifidobacterium breve | 1.83 |
| Clostridium butyricum | 1.78 |
| Faecalibacterium prausnitzii | 1.73 |
| Streptococcus thermophilus | 1.54 |
| Bifidobacterium bifidum | 0.89 |
| Bifidobacterium catenulatum | 0.8 |
| Ruminobacter amylophilus | 0.55 |
| Bifidobacterium animalis | 0.51 |
| Bifidobacterium pseudocatenulatum | 0.51 |
| Enterococcus durans | 0.47 |
| Lactobacillus johnsonii | 0.4 |
| Leuconostoc mesenteroides | 0.33 |
| Roseburia faecis | 0.32 |
| Veillonella atypica | 0.23 |
| Lacticaseibacillus paracasei | 0.2 |
| Phocaeicola coprophilus | 0.18 |
| Bacillus velezensis | 0.08 |
| Lactobacillus acidophilus | -0.05 |
| Bacteroides thetaiotaomicron | -0.23 |
| Bacteroides uniformis | -0.3 |
| Limosilactobacillus reuteri | -0.3 |
| Bacillus amyloliquefaciens group | -0.3 |
| Lentilactobacillus parakefiri | -0.31 |
| Phocaeicola dorei | -0.32 |
| Bacillus subtilis group | -0.32 |
| Limosilactobacillus vaginalis | -0.32 |
| Enterococcus faecium | -0.33 |
| Bacillus subtilis | -0.7 |
| Lactobacillus helveticus | -0.85 |
| Lactobacillus jensenii | -0.85 |
| Pediococcus acidilactici | -1.05 |
I should note that Pediococcus acidilactici is a high take for Light Sensitivity and a take for MCS for the light sensitive person. It is a to be avoided for the Anchorite in both cases. This goes back to the old saying “No probiotics can serve two people with the same symptoms” (Matt 6:24, Microbiome Translation).
Take Suggestions
These match the general pattern seen for Long COVID and ME/CFS
| Modifier | Net | Take | Avoid |
| (2->1)-beta-D-fructofuranan {Inulin} | 133 | 137 | 4 |
| dietary fiber | 82 | 106 | 25 |
| oligosaccharides {oligosaccharides} | 78 | 90 | 12 |
| Slow digestible carbohydrates. {Low Glycemic} | 77 | 106 | 29 |
| Fiber, total dietary | 69 | 91 | 21 |
| fruit | 60 | 80 | 21 |
| Lactobacillus plantarum {L. plantarum} | 50 | 67 | 18 |
| fruit/legume fibre | 48 | 67 | 19 |
| fructo-oligosaccharides | 48 | 51 | 3 |
| synthetic disaccharide derivative of lactose {Lactulose} | 46 | 48 | 2 |
| Human milk oligosaccharides (prebiotic, Holigos, Stachyose) | 38 | 46 | 8 |
| Cichorium intybus {Chicory} | 36 | 39 | 3 |
| wheat | 35 | 40 | 6 |
| Hordeum vulgare {Barley} | 34 | 44 | 11 |
| whole-grain diet | 33 | 46 | 13 |
| ß-glucan {Beta-Glucan} | 33 | 38 | 5 |
| High-fibre diet {Whole food diet} | 32 | 48 | 16 |
| Bovine Milk Products {Dairy} | 32 | 46 | 13 |
| resistant starch | 32 | 40 | 8 |
Avoid Suggestions
We have a few herbs or spices showing up as an avoid. When we look at MCAS, we see a very atypical avoid list.
| Modifier | Net | Take | Avoid |
| Ferrum {Iron Supplements} | -26 | 4 | 30 |
| high-fat diets | -15 | 9 | 24 |
| Ethyl alcohol {Grain alcohol} | -8 | 3 | 10 |
| high red meat | -7 | 0 | 8 |
| 5,6-dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium {Berberine} | -7 | 11 | 18 |
| Nitrogen Oxide x Particulate Matter {Urban air pollutant} | -6 | 2 | 8 |
| High-protein diet {Atkins low-carbohydrate diet} | -6 | 4 | 10 |
| vegetarians | -6 | 4 | 10 |
| low fodmap diet | -6 | 8 | 15 |
| Azadirachta indica {Neem} | -4 | 0 | 4 |
| Silver nanoparticles {Colloidal silver} | -4 | 0 | 4 |
Summary
The new offering is easy to use, just follow the video above. Remember, most symptoms are caused by combinations of bacteria that alters the metabolites (chemicals) that the body gets. There are many distinct combinations that can produce a symptom. Above is NOT a general guidance, it shows the results for a specific person using their microbiome. The suggestions for your microbiome may be different. Testing is not optional if you want to make progress.