Probiotics Fundamentals: Part 4 Probiotic Selection?

Related posts:

In the first post of this series, Probiotics Fundamentals: Part 1 Specific Strains I cited strains that are available retail that has been researched. The logical starting point is to search for your needs, read the studies and then rank the probiotics in prefer order for doing a personal trial. You want to do one probiotic at a time with rotation and described in the prior post (see prior post).

To searching for strain specific studies of probiotics available retail. Click here.

No Study found or issue not listed

The next step is to look at the conditions that I have abstracted/extracted studies for, listed at “U.S. Nat. Lib. Medical Conditions Studies with Microbiome Shifts“. We are shifting from strain to species level. This gives several paths, let us examine Autism. There are

Based on Publish Studies of Species

Clicking on [Can You Help Improve Suggestions] will take you to a page. At the bottom you will see “Treatment Substances” which lists things that have helped in studies. Scan it for probiotic names, for example:ā€ƒ

A synbiotic formulation of Lactobacillus reuteri and inulin alleviates ASD-like behaviors in a mouse model: the mediating role of the gut-brain axis. Food & function (Food Funct ) Vol: 15 Issue: 1 Pages: 387-400 Pub: 2024 Jan 2 ePub: 2024 Jan 2 Authors Wang C,Chen W,Jiang Y,Xiao X,Zou Q,Liang J,Zhao Y,Wang Q,Yuan T,Guo R,Liu X,Liu Z

Which suggests L. Reuteri with inulin may help. The source is linked. Make sure you read them.

Based on Deficiencies of Probiotic Bacteria

Clicking on 🦠 Taxons will take you to a page showing all of the bacteria shifts reported for the condition.

Look for Lactobacillus, Bifidobacterium,etc  with  ā¬‡ļø

These species are found at lower levels, suggesting their metabolites are also reduced. Supplementing with them as single-strain probiotics is logical. Stay at the species level (e.g., Bifidobacterium longum) rather than higher classifications such as the genus Bifidobacterium. In general, avoid probiotic mixtures, as they may include strains that are counter-indicated (e.g., Bifidobacterium catenulatum, Bifidobacterium breve) or strains for which we lack sufficient information.

Based on Modelled correction of Bacteria

Clicking on 🄣 Candidates, will send the huge bacteria list above through a fuzzy logic expert system to compute suggestions with weights given for each one.

Note that this also lists ones to avoid.

Disagreements!

We can see that levels of Lactobacillus plantarum are low, but the model is telling us to avoid Lactobacillus plantarum. So what’s going on here?

The issue comes from the fact that the model/studies is based on multiple subgroups of people with Autism (or other conditions). The data might be accurate within each subgroup, but when you merge them together, you can end up with contradictions. So it’s not really a problem with the approach—it’s a problem with the data mix.

The best rule of thumb is to start with the things that show up as agreements across the data. For example: Bifidobacterium longum and Limosilactobacillus reuteri. Once you’ve tried probiotics that have clear agreements, then you can carefully experiment with the ones where there’s disagreement and see how your body responds.

The next level up in Probiotic Suggestions

It is pretty simple, get a microbiome test. My preferred tests are:

  • Biomesight for 16s (economic, low resolution)
  • Thorne for shotgun (more expensive but much higher detail)

You want to ideally get a test that reports on all of the common probiotic bacteria. Many common tests do not report many of these. For example: Diagnostic Solution GI-Map reports only

On the other hand both of the above tests report species.

When you select a test, you should check Microbiome Prescription to see what the detection rate is. For example for Bifidobacterium longum, we see how often this is detected in samples.

  • For the shotgun tests (Xenogene and Thorne) we see 96% and 100% of the time, if it show low, you can have confidence in taking some
  • For SequentiaBiotech we see it is seen 25% of the time. If you have none reported we are left being uncertain if you actually have none or is the none because of the test’s methodology

Another example is L.Reuteri where the shotgun tests find in in over 50% of samples, while some 16s finds in only 2% of samples.

Bottom Line

We’re piecing things together from lots of scattered knowledge, and there’s no single standard method—either for testing microbiomes in labs or for the studies themselves. Nothing here is clear-cut; everything’s kind of fuzzy, sometimes super fuzzy. In this post, the focus was on picking probiotics for a condition using literature (an ā€œa prioriā€ approach). Basically, it means trusting the data at face value, even though we know it isn’t rock-solid.

Some additional readings:

I also foreshadowed the next post: Using a detailed microbiome test to select probiotics based on the whole microbiome.

Opinion: GTDB should be blacklisted for Clinical Use

I believe it is the consumer interest to share this email thread and to promote discussion of this issue.

Blacklisting is the action of suggesting something to be avoided or distrusted.

Request

[Customer name withheld] has forwarded me the PDF and some CSV files associated. She wishes to see what the recommendations from a fuzzy logic expert system that uses over 7.4 million facts based on data from the US National Library of Medicine will suggest.

 I know that the following data is very much available and possible to provide. Other firms like Biomesight.com, Thorne, Vitract and Precision Biome has no trouble providing it:

For all taxonomical layers (From Clade to strains [when available]) just 3 numbers are sufficient.

  • NCBI Taxon Number, 
  • Percentage Amount, 
  • Percentile Ranking across a reference set of healthy individuals

Additional data is welcome, but not required:

  1. Names
  2. Your reference ranges 
  3. etc

Percentiles should be actual percentiles and NOT percentiles estimated using mean and standard deviation. Most bacteria has a SKEW exceeding 20. Using the mean and average requires a SKEW of zero.

Your customer would greatly appreciate a speed return of an appropriate file. With that file in hand, we will add your lab to our list of over 50 labs that our free site supports. (See https://microbiomeprescription.com/Upload/Index ).

If you are unable to provide such, please tell us so we may black list your site as not supportable to spare other consumers a waste of money.

Response

Hi Ken,
Thank you for your detailed email and for sharing your perspective on the data formats and metrics you require.

We’d like to clarify that Microba uses the Genome Taxonomy Database (GTDB) for microbial classification. GTDB and NCBI classify genomes differently, our species consist of multiple genomes which may have different NCBI classifications, species level classifications cannot always be mapped to each other through name matching alone. Due to this, providing a microbiome profile in NCBI taxonomy is not practical nor would it be a correct representation of the actual microbiome profile.

Once GTDB is formally supported within your workflow, please reach out and we can discuss options for providing the data your service requires.

We appreciate your understanding and encourage you to support the more accurate, resolved, and phylogenetically consistent GTDB taxonomy.

Kind regards,
The Microba Team

Reply To Response

Many thanks for your reply. Our purpose is to provide clinical suggestions for review by medical professionals to people suffering from a wide variety of conditions using hallucination-free AI.

A simple example may be seen here. DepressionExample.

Unfortunately, Genome Taxonomy Database(GTDB) appears to be a research tool and IMHO seems very inappropriate and misleading to sell to consumers. GTD was first proposed in academic papers in August 2018. We were active in the microbiome before that and the de facto standard in the industry as then, and still is today, the NCBI. The leading consumer microbiome testing company back then was uBiome which provided NCBI identifiers. In the 7 years since first release, we have seen what appears to be some 226 revisions given the release of   10-RS226, dated April 16, 2025.

Checking the US National Library of Medicine, there appears to be less than 200 studies done using GTDB that are of likely clinical use. With NCBI, we found over 20,000 suitable studies. Regardless, no study done prior to 2020, likely 2022, can, in a legal sense, be safely used for clinical purposes. 

I am aware of many tools to convert GTDB to NCBI, a few are:

  • TaxonKit: Command-line toolkit that supports creating NCBI-style taxdump files from GTDB and also reformatting and mapping taxonomies.
  • gtdb_to_taxdump: Python tool to convert GTDB taxonomy files into NCBI taxdump format, usable by downstream tools like Kraken2.
  • GTDB-Tk: Assigns genomes to GTDB taxonomy but includes metadata fields mapping to NCBI taxonomy, enabling conversion between formats.
  • NCBI-GTDB Map: Direct tool for mapping GTDB taxonomy to NCBI taxonomy, supporting both directions and handling rank prefixes.
  • gtdb-taxdump: A specialized toolkit for generating stable, trackable NCBI taxdump files from GTDB releases with reproducible taxon IDs.
  • NCBI-taxonomist: Python command-line utility that retrieves, handles, and allows mapping of taxonomic information, supporting cross-database operations.

I am aware that folks embracing the hottest new technology can have an attitude, especially when most recent studies decline to use it. Intransient on this issue is not beneficial to your customers; people with challenging health issues unless you are willing to provide a GTDB based suggestions engine working off only GTDB studies,Ā 

hallucination-free AI that is equivalent or better than what NCBI can provide. Until such time, I would advocate that you stop making misleading sales to consumers.

Given your response, I feel that I have no option back to blacklist you for clinical use.

Probiotics Fundamentals: Part 3 Are they working?

Related posts:

From years of using different probiotics, I have developed some simple rules of thumbs on the use of probiotics. These rules have worked very well with probiotics from my favorite source: Maple Life Scienceā„¢. Their probiotics show both manufacture date and expiry date. Typically they arrive within a month of the manufacture date direct from the manufacturer. IMHO, high probability from being alive at arrival.

Do one Species at a time

Maple Life Scienceā„¢ probiotics are usually single species with just FOS as an additive. My usual preference is taking probiotic powder dissolved in warm water at least one hour away from any meals. Bacteria in your gut has to enter somewhere — and that location is the mouth. You may want to also alter your mouth microbiome so it is less likely to repopulate your gut bacteria with undesirables.

My typical pattern is doing one probiotic for 2 weeks and then rotate to another. See below for the rationale.

How do I know that they are different probiotics?

I could send them off for testing, but what I have observed is this:

  • They are often slightly different colors
  • They tastes differently

I do not know definitively if they are as claimed, but I do see that they are different.

Are there any changes within a week?

I monitor myself after starting each probiotics. I expect at least one of the following to change:

  • Smell of farts
  • Number of farts
  • Frequency of stools
  • Characteristics of stools using the Bristol stool chart
  • Changes on my smart watch monitoring
  • Changes of sleep patterns
  • Change of eating habits/food preferences
  • Changes of mood or alertness

If there are no changes, then I label the bottle as “No effect” and put it at the back of the refrigerator shelf. To me, probiotics should change the microbiome is some observable way. The above are indicators of change. This does take some self-awareness of each.

Personal Example: My wife has Crohn’s disease. Whenever she starts to have a flare, she takes Mutaflor (E.Coli Nissle 1917) probiotics and within 1-2 hours the flare ends. Probiotics impact should be apparent in hours or a few days.

Dosages titration

When I try a new probiotic, I usually start with the standard dosage. If there are no apparent change happening in 3 days, I double the dosage (and keep doubling every 3 days for up to 14 days). In practical terms:

  • Day 1: 1 capsule
  • Day 4: 2 capsules
  • Day 7: 4 capsules
  • Day 10: 8 capulses
  • Day 13: 16 capsules

The logic is simple: there may be less viable bacteria (for some reason) and thus more capsules are needed to get effective dosages to induce a change.

Probiotic Rotation

To me, the purpose of probiotics is to change the microbiome, typically, a dysbiosis. The metabolites and bacteriocins being produced by the probiotics will alter the population by either increasing metabolites that may feed (increase) other bacteria or decrease other bacteria by the bacteriocins. In other words, I view the probiotics as a course correction around a reef.

Bacteriocins Resistance

Bacteriocins are natural antibiotics. Many antibiotics are derived from bacteriocins. This means that bacteriocins resistance needs to be considered. Typically, most of the targeted bacteria has some bacteria that are resistant to some form of antibiotics. These resistors will prosper because their sibling competitors are no longer there. I have read several studies that found pulsed or rotated antibiotics were more effective than continuous antibiotics. My take away is simple: “a course of probiotics” followed by rotation. How long should the course be? I take the duration from the typical duration of prescribted antibiotics (10-14 days).

Some known bacteriocins are listed below

  1. Nisin ā€“ produced by Lactococcus lactis.
  2. Pediocin PA-1/AcH ā€“ produced by Pediococcus acidilactici.
  3. Enterocin AS-48 ā€“ produced by Enterococcus faecalis.
  4. Colicin A ā€“ produced by Escherichia coli.
  5. Colicin E1 ā€“ produced by Escherichia coli.
  6. Microcin J25 ā€“ produced by Escherichia coli.
  7. Plantaricin E ā€“ produced by Lactobacillus plantarum.
  8. Plantaricin F ā€“ produced by Lactobacillus plantarum.
  9. Leucocin A ā€“ produced by Leuconostoc gelidum.
  10. Helveticin I ā€“ produced by Lactobacillus helveticus.
  11. Lactocin MXJ 32A ā€“ produced by Lactobacillus coryniformis.
  12. Enterolysin A ā€“ produced by Enterococcus faecalis.
  13. Salivaricin ā€“ produced by Lactobacillus salivarius.
  14. Pyocin S2 ā€“ produced by Pseudomonas aeruginosa.
  15. Microcin E492 ā€“ produced by Klebsiella pneumoniae.
  16. Lactococcin G ā€“ produced by Lactococcus lactis.
  17. Plantaricin JK ā€“ produced by Lactobacillus plantarum.
  18. Plantaricin EF ā€“ produced by Lactobacillus plantarum.
  19. Goadsporin ā€“ produced by Streptomyces sp..
  20. Plantazolicin ā€“ produced by Bacillus amyloliquefaciens.

Some antibiotics obtained from bacteria:

  1. Streptomycin ā€“ from Streptomyces griseus
  2. Chloramphenicol ā€“ from Streptomyces venezuelae
  3. Tetracycline ā€“ from Streptomyces rimosus and Streptomyces aureofaciens
  4. Erythromycin ā€“ from Saccharopolyspora erythraea (formerly Streptomyces erythraeus)
  5. Neomycin ā€“ from Streptomyces fradiae
  6. Lincomycin ā€“ from Streptomyces lincolnensis
  7. Rifamycin ā€“ from Amycolatopsis rifamycinica (previously Streptomyces rifamycinica)
  8. Vancomycin ā€“ from Amycolatopsis orientalis
  9. Bacitracin ā€“ from Bacillus subtilis and Bacillus licheniformis
  10. Gramicidin ā€“ from Bacillus brevis
  11. Polymyxin B ā€“ from Bacillus polymyxa
  12. Teicoplanin ā€“ from Actinoplanes teichomyceticus
  13. Fusidic acid ā€“ from Fusidium coccineum (a fungus, included due to bacterial-related antibiotic use)
  14. Novobiocin ā€“ from Streptomyces niveus
  15. Ristocetin ā€“ from Amycolatopsis lurida
  16. Mupirocin ā€“ from Pseudomonas fluorescens
  17. Tyrocidine ā€“ from Bacillus brevis
  18. Clavulanic acid ā€“ from Streptomyces clavuligerus
  19. Daptomycin ā€“ from Streptomyces roseosporus
  20. Carbapenems (e.g., Imipenem) ā€“ from Streptomyces species and related bacteria

Bottom Line

The bottom line is simple: rotate and note changes. If there are no changes,

Probiotics Fundamentals: Part 2 DOA on Shelf

Related posts:

Below you see some data information shown on a few probiotic products. Many products do not show either production date nor best by date. They are not legally required.

My preference has always favor probiotics that includes manufacturing date. Two of the products above cite a three year shelf life (assuming appropriate storage). My favorite source, Maple Life Scienceā„¢, ship directly to me from their factory. Usually they arrive within one month of manufacture (occasionally, the same month!)

Some Studies of special interest

The chart below is from Study of Viability, Storage Stability, and Shelf Life of Probiotic Instant Coffee Lactiplantibacillus plantarum Subsp. plantarum Dad-13 in Vacuum and Nonvacuum Packaging at Different Storage Temperatures [2022]

From the moment that a probiotic leaves a factory, temperature control is usually non-existent. The trucks that transport them are likely not refrigerated nor are wholesale warehouse storing them. When they arrive at a health food store they are typically placed in a refrigerated cabinet for presentation to customers. In many cases, if you insist on seeing where the bottles are stored before, do not be surprise to see that it is not a refrigerated area. It is possible that the probiotics may be subject to 37C(98.6F) for months before the shop keeper places it in the refrigerated cabinet. Each number on the left scale indicate 1/10 of the number above it.

A shipment from a east coast producer to a west coast store direct, is 4-8 days. If the shipment goes to a wholesaler’s warehouse than expect a few days more. The result in summer can easily be as much as 97% of the viable bacteria that leaves the factory may be killed if it takes 15 summer days (per above chart).

From Perplexity.ai, this is clear:

The short version is that during summer in the US, the amount of viable bacteria may be 1/100 of what the probiotic had at the factory. There are stick-on labels that will change color if storage exceeds a threshold — unfortunately, no one is using that.

Microbiological Quality and Antimicrobial Resistance of Commercial Probiotic Products for Food-Producing Animals [2024] reports no viable Lactobacillus was found in some products 

In terms of probiotics sold by microbiome testing companies, the only one that I know of that “ships direct from probiotic manufacturer” is PrecisionBiome.Eu that has established a relationship with a German probiotic producer. Their client base is the EU, so transit time from “vat to customer” is short.

Absence of Regulations Problem

There are recommendations such as Best Practices Voluntary Guidelines for Probiotics[2017] provides some guidance (ignored by most producers). Producers can make claims of shelf life (best before) of 10 years without consequences. With no manufacture date, no one knows when it was made. Calls to their customer lines will usually give questionable answers. The probiotic industry have many active lobbyists to inhibit anything that may effect profits.

Figure Pointing for Probiotics being DAO

If you buy a probiotic and found it is effectively DAO and contact the manufacturer. The manufacturer will claim no responsibility once it left their premise. It is the responsibility of the trucking companies and wholesaler storage. Those folks will then point at the retail store mishandling things.

This harsh reality is why I try to buy direct from the manufacturer (no Amazon, no health food stores).

Bottom Line

“I didn’t get any benefit from probiotics, I got them refrigerated from my trusted health food store is a frequent complaint that I hear. IMHO, they do not work because they have been well cooked! Our habit is order our year supply of probiotics from Maple Life Scienceā„¢ in the fall and winter. The colder it is outside, the better it is.

My “rules of thumbs” on taking probiotics will be the next topic.

Probiotics Fundamentals: Part 1 Specific Strains

Other post in this theme:

What is the difference between a Species and a Strain? To understand this, view Species as “dogs” and strains as specific types. Is picking a Chihuahua as a police dog a good choice, or a St. Bernard suitable for someone with disability living in a one room apartment?

The chart below shows different aspects of different strains for Lactobacillus Reuteri. When you buy a probiotic names “Lactobacillus Reuteri”, it is unlikely which species if was obtained from is specified on the bottle. If it was not from a human, it is very unlikely that it will reproduce or take root in your body.

Probiotic manufacturers and packagers are focused on making money. They will ask for the cheapest source for a probiotic that they expect to be able to sell for the greatest profit. Human source is not a factor, cheapness is!

I have known people that are histamine sensitive that are fine with one brand of Lactobacillus Reuteri but get sick from another brand…. Looking at the chart below, the answer is obvious: One has a histamine producer and one does not.

From prediction to function using evolutionary genomics: human-specific ecotypes of Lactobacillusreuteri have diverse probiotic functions[2014].

Researched but not for sale

This morning I was asked about Bacteroides fragilis BF839 which is cited in several studies on the US National Library of Medicine. Most of the studies are from 2024 or 2025. At present, it is not for sale anywhere and I do not expect it to be for five(5) years at least because of approval processes. Given the authors’ location, I expect it will be first available in China.

Researched and Stain is for sale šŸ™‚

Several years ago I set up a free page listing those available (somewhere in the world). I also automated a weekly automatic scan of the US National Library of Medicine for any new studies using these strains. The page is kept up to date.

Occasionally, someone emails me about a new strain that has one or more studies associated. I add those to the list. If you find one that I missed, please email me!

The page allows searching across the studies abstracts for key words. For example, if you are interested in Autism, just enter that and click search. The page will then show the retail brands with links to the studies.

The intent of the page is discourage random trial of probiotics which has no effect (except on bank accounts).

List of Strains with name of product or seller

At present we are at 156 different strains. These are listed below.

  • Akkermansia muciniphila WB-STR-0001: Pendukum Glucose Control
  • Aspergillus oryzae NK: strong wakamoto w
  • Bacillus clausii MCC 0538: Biome Ultra
  • Bacillus clausii N/R: Enterogermina
  • Bacillus clausii O/C: Enterogermina
  • Bacillus clausii SC-109: MegaSporebiotic
  • Bacillus clausii SIN: Enterogermina
  • Bacillus clausii T: Enterogermina
  • Bacillus coagulans ATCC 5856: Nature’s Sunshine Bacillus Coagulans,
  • Bacillus coagulans DSM 17654: Biome Ultra
  • Bacillus coagulans GBI-30: SchiffĀ® Digestive AdvantageĀ® Daily Probiotic
  • Bacillus coagulans SC-208: MegaSporebiotic
  • Bacillus coagulans SC208: Eded 3 in 1
  • Bacillus Coagulans SNZ1969: Jetson FIT
  • Bacillus coagulans Unique IS-2: Optibac Probiotics Adult Gummies Probiotics
  • Bacillus indicus HU36: MegaSporebiotic
  • Bacillus licheniformis DSM5749: PrecisionBiome
  • Bacillus mesentericus (subtilis) TO-A: AOR, Probiotic 3
  • Bacillus subtilis ATCC SD 7280: Biome Ultra
  • Bacillus subtilis BG01-4TM: VERNX
  • Bacillus subtilis DE111 : Probiotic w/ DE111
  • Bacillus subtilis DSM17299: PrecisionBiome
  • Bacillus Subtilis HU58: MegaSporebiotic
  • Bacillus Subtilis MB40: Country Farms Super Flora Probiotics
  • Bacteroides xylanisolvens DSM 23964: AVI-1 (pending on market)
  • Bifidobacterium adolescentis IVS-1: Synbiotic Health ISV-1
  • Bifidobacterium adolescentis PRL2019: Gabapral
  • Bifidobacterium animalis ssp. lactis 420: UltraFloraĀ® Control
  • Bifidobacterium animalis ssp. lactis CUL-34 (NCIMB 30153): Genestra Brands – HMF Neuro Powder
  • Bifidobacterium animalis subsp lactis HN019: Optibac Every Day Max
  • Bifidobacterium animalis subsp. lactis CECT 8145: Culturelle Healthy Metabolism + Weight Management Supplement
  • Bifidobacterium bifidum BB-06: Custom Probiotics
  • Bifidobacterium bifidum CUL-20 (NCIMB 30172) : Genestra Brands – HMF Neuro Powder
  • Bifidobacterium bifidum G9-1 (BBG9-1): Phillips’Ā® Colon Health
  • Bifidobacterium bifidum HA-132: Human Probiotics
  • Bifidobacterium bifidum MIMBb75 (SYN-HI-001): IRRITABLE COLON PRO KIJIMEA
  • Bifidobacterium bifidum W23: EcologicĀ® Barrier for Metabolic Health
  • Bifidobacterium breve HA-129: Human Probiotics
  • Bifidobacterium Breve LMG 11613: Bioflora (Mexico)
  • Bifidobacterium breve M-16V: Optibac Probiotics Professional
  • Bifidobacterium breve PRL2020: PharmExtracta / Brevicillin Stick
  • Bifidobacterium lactis BB-12: NestlĆ©
  • Bifidobacterium lactis Bi-07: UltraFloraĀ® Balance
  • Bifidobacterium lactis Bl-04: Optibac Probiotics Every Day MAX Probiotics
  • Bifidobacterium lactis BL-4: Custom Probiotics
  • Bifidobacterium lactis W51: EcologicĀ® Barrier for Metabolic Health
  • Bifidobacterium lactis W52: EcologicĀ® Barrier for Metabolic Health
  • Bifidobacterium longum 1714: ZenfloreĀ®
  • Bifidobacterium longum 35624: Align
  • Bifidobacterium longum BB536: Probiotic Pro Bb536
  • Bifidobacterium longum BL-05: Custom Probiotics
  • Bifidobacterium longum ES1: PharmExtracta / Gliadines buccal stickpacks
  • Bifidobacterium longum MM-2: Phillips’Ā® Colon Health
  • Bifidobacterium longum R0175: Calm BioticĀ®
  • Bifidobacterium longum ssp. infantis R0033: Human Probiotics
  • Bifidobacterium longum ssp. longum HA-135: Human Probiotics
  • Bifidobacterium longum subsp. infantis Bi-26: Custom Probiotics
  • Bifidobacterium longum subsp. infantis NLS: Life Start 2
  • Bifidobacterium longum Subspecies infantis Strain EVC001: EvivoĀ® Infant Probiotic Powder
  • Bifidobacterium longum W108: EcologicĀ® Relief
  • Bifidobacterium longum W11: PharmExtracta / Bowell
  • Clostridium Butyricum MIYAIRI: Miyarisan
  • Clostridium butyricum TO-A: AOR, Probiotic 3
  • Clostridium butyricum WB-STR-0006 : Pendukum Glucose Control
  • Enterococcus faecalis T-110: AOR, Probiotic 3
  • Enterococcus faecium L3: PharmExtracta / INatal Sachets
  • Enterococcus faecium SBS 1: Shin Biofermin S
  • Enterococcus faecium SF 68: Bioflorin
  • Enterococcus faecium W54: EcologicĀ® AAD
  • Escherichia coli , Laves strain 1931: Colibiogen
  • Eubacterium hallii WB-STR-0008: Pendukum Glucose Control
  • Hafnia alvei HA4597: SymbioLife Ā® Satylia
  • Heat Killed Lactobacillus plantarum L-137: Swanson Immunobiotic Immuno-LP20
  • Lacticaseibacillus paracasei subsp. paracasei CNCM I-1518: DanActive
  • Lacticaseibacillus rhamnosus HN001: Optibac Probiotics Babies & Children Probiotics
  • Lactobacillus acidophillus CUL-21 (NCIMB 30156): Genestra Brands – HMF Neuro Powder
  • Lactobacillus acidophilus ATCC 4356: resBĀ® Lung Support
  • Lactobacillus acidophilus CL1285: Bio-K+
  • Lactobacillus acidophilus CUL-60 (NCIMB 30157): Genestra Brands – HMF Neuro Powder
  • Lactobacillus acidophilus HA-122: Human Probiotics
  • Lactobacillus acidophilus LA-14: Custom Probiotics
  • Lactobacillus Acidophilus LA1: Flora Pro Fem with Cranberry
  • Lactobacillus acidophilus NCFM: UltraFloraĀ® Balance
  • Lactobacillus acidophilus W22: Ecologic Performance
  • Lactobacillus acidophilus W37: EcologicĀ® Barrier for Metabolic Health
  • Lactobacillus acidophilus W55: EcologicĀ® Allergycare
  • Lactobacillus brevis W63: EcologicĀ® Barrier for Metabolic Health
  • Lactobacillus casei LBC80R: Bio-K+
  • Lactobacillus casei LC-11: Custom Probiotics
  • Lactobacillus casei R0215: PharmExtracta / INatal Sachets
  • Lactobacillus casei Shirota: Yakult
  • Lactobacillus casei W56: EcologicĀ® Barrier for Metabolic Health
  • Lactobacillus casei W79: EcologicĀ® Relief
  • Lactobacillus crispatus LbV 88 (DSM 22566): AZO Complete Feminine Balance
  • Lactobacillus fermentum ME-3: Reg’Activ Essential ME-3
  • Lactobacillus gasseri KS-13: Phillips’Ā® Colon Health
  • Lactobacillus gasseri LbV 150N (DSM 22583): AZO Complete Feminine Balance
  • Lactobacillus Gasseri LMG 266: Bioflora (Mexico)
  • Lactobacillus gasseri SBT2055: gasseri SP strain capsule
  • LACTOBACILLUS HELVETICUS L10: LACTOBACILLUS HELVETICUS LAFTIĀ® L10
  • Lactobacillus helveticus R0052: Calm BioticĀ®
  • Lactobacillus jensenii LbV 116 (DSM 22567): AZO Complete Feminine Balance
  • Lactobacillus Kefiri LKF01 (DSM 32079) LKEF : Kefibios
  • Lactobacillus paracasei (case)i 431: For daily immunity
  • Lactobacillus paracasei 8700:2: UltraFloraĀ® Cold Support
  • Lactobacillus paracasei F-19: Optibac Probiotics For Women Probiotics
  • Lactobacillus paracasei Lpc-37: Custom Probiotics
  • Lactobacillus paracasei W20: EcologicĀ® AAD
  • Lactobacillus plantarum 299v: Jarrow Formulas Ideal Bowel Support
  • Lactobacillus plantarum DR7: SymbioLact Ā® Pro Sleep
  • Lactobacillus plantarum HEAL9: UltraFloraĀ® Cold Support
  • Lactobacillus plantarum Lp-115: Custom Probiotics
  • lactobacillus plantarum LP45: Natealth
  • lactobacillus plantarum ps128: Neurobiotique PS128
  • Lactobacillus plantarum W1: Winclove Senior
  • Lactobacillus plantarum W21: Ecologic Travel
  • Lactobacillus plantarum W62: EcologicĀ® AAD
  • Lactobacillus reuteri ATCC PTA 5289: BioGaiaĀ® ProDentis
  • Lactobacillus reuteri DSM 17938: BioGaiaĀ®
  • Lactobacillus reuteri RC-14: RepHreshā„¢ Pro-Bā„¢ Probiotic
  • Lactobacillus rhamnosus CLR2: Bio-K+
  • Lactobacillus rhamnosus GG: CulturelleĀ®
  • Lactobacillus rhamnosus GR-1: RepHreshā„¢ Pro-Bā„¢ Probiotic
  • Lactobacillus rhamnosus HA-111: Human Probiotics
  • Lactobacillus rhamnosus LbV96 (DSM 22560): AZO Complete Feminine Balance
  • Lactobacillus rhamnosus Lcr35: ProvacareĀ®
  • Lactobacillus rhamnosus Lr-32: Custom Probiotics
  • Lactobacillus rhamnosus LR1: Flora Pro Fem with Cranberry
  • Lactobacillus rhamnosus R0011: Flora Pregnancy Care Probiotic
  • Lactobacillus rhamnosus W71: EcologicĀ® AAD
  • Lactobacillus Sakei pro-Bio-65: Kimchi Power
  • Lactobacillus salivarius HA-118: Human Probiotics
  • Lactobacillus Salivarius Ls-33: Custom Probiotics
  • Lactobacillus salivarius UCC118: UltraFloraĀ® Integrity
  • Lactobacillus salivarius W24: EcologicĀ® Barrier for Metabolic Health
  • Lactocaseibacillus rhamnosus ATCC 53103: resBĀ® Lung Support
  • Lactococcus lactis JCM5805 (L. lactis plasma): IMMUNOFLORA
  • Lactococcus lactis LL-23: Custom Probiotics
  • Lactococcus lactis W19: EcologicĀ® Barrier for Metabolic Health
  • Lactococcus lactis W58: EcologicĀ® Barrier for Metabolic Health
  • Lactoplantibacillus plantarum ATCC BAA-793: resBĀ® Lung Support
  • Limosilactobacillus reuteri SD5865: Natures-Way-Primadophilus-Reuteri-Pearls
  • Mutaflor (Escherichia coli strain Nissle 1917): Mutaflor (Canada, Australia, Findland, Germany)
  • Oxalobacter formigenes DSM 4420: TrueMeds
  • Pediococcus Acidilactici NRRL B-50517: Imagilin Nutri-5051
  • Prescript Assist(multi species): Prescript Assist (dispute on formula change)
  • Propionibacterium freudenreichii shermanii : Optim Propionibacter
  • Saccharomyces boulardii (Klaire Labs): Klaire Labs Saccharomyces boulardii
  • Saccharomyces boulardii CNCM I-745: FlorastorĀ®
  • Saccharomyces Boulardii THT 500101: Bioflora (Mexico)
  • Saccharomyces cerevisiae boulardii CNCM I-1079: Pure Encapsulations
  • Streptococcus salivarius K12: BLIS ThroatHealth Oral Probiotics
  • Streptococcus thermophilus ST-21: Custom Probiotics
  • Symbioflor 1: German Apotheke by Paul’s Mart
  • Symbioflor 2: German Apotheke by Paul’s Mart
  • VSL3 / Visbiome / De Simone Formulation: Alfasigma USA, Inc.

Safest Product for Correct Identification

These strains are usually under legal protection and thus the manufacturer has a vested (financial) interest to make sure that “what is advertised is delivered”.

Why is this important, just look at some of the literature

Your first choice should be the probiotics strains that are most likely to be as advertised and has been studied for the symptom of condition that you are interested in.