Some 3 years ago, in this post I update my earlier post from 2013 and cited “, it is my hypothesis that this alters the microbiome — how, has still to be reported. “. There has been no objective impact on the human microbiome reported yet :-(.

Assuming that depression is partially microbiome caused (see this list of bacteria shifts seen with depression) then we have circumstantial evidence that they are changes (but do not know the details in humans). We do have information from one study on mice (see bottom of post)

• Feasibility and acceptability of a Whole-Body hyperthermia (WBH) protocol [2021] i.e. positive results for treatment for major depressive disorder 
• Whole-Body Hyperthermia for the Treatment of Major Depressive Disorder: A Randomized Clinical Trial. [2016]
• The impact of whole-body hyperthermia interventions on mood and depression – are we ready for recommendations for clinical application? [2019]
• Changes in mood state following whole-body hyperthermia. [2992]
• Far-infrared Ray-mediated Antioxidant Potentials are Important for Attenuating Psychotoxic Disorders. [2019]
  • ” FIR requires modulations of janus kinase 2 / signal transducer and activator of transcription 3 (JAK2/STAT3), nuclear factor E2- related factor 2 (Nrf-2), muscarinic M1 acetylcholine receptor (M1 mAChR), dopamine D1 receptor, protein kinase C δ gene, and glutathione peroxidase-1 gene for exerting the protective potentials in response to neuropsychotoxic conditions.”
• Far infrared radiation induces changes in gut microbiota and activates GPCRs in mice [2019]

Needless to say, the later information has been added to suggestions algorithms.